Skip to product information
1 of 1


DNase I, RNase-free (50 U/µl)

DNase I, RNase-free (50 U/µl)

Regular price 27.800 Ft
Regular price Sale price 27.800 Ft
Sale Sold out

In stock

Download Manual PDF

Deoxyribonuclease I (DNase I) is an endonuclease that digests single- or double-stranded DNA. It recognizes and cleaves phosphodiester bonds to produce a single deoxynucleotide or single- or double-stranded oligodeoxynucleotide with 5'-phosphorylated and 3'-hydroxylated ends. The activity of DNase I depends on Ca2+, and DNase I can also be activated by divalent metal ions such as Mg2+ and Mn2+. In the presence of Mg2+, DNase I nonspecifically recognizes and cleaves a double-stranded DNA at any site on either strand, and in the presence of Mn2+, it recognizes and cleaves almost the same sites on both strands of the DNA to produce DNA fragments with blunt ends or sticky ends with one or two nucleotide overhangs.

Shipping and Storage

Store at -30 ~ -15°C and transport at ≤0°C.


Collapsible row

View full details