Hyperactive ATAC-Seq Library Prep Kit for Illumina is a kit developed specifically for the Illumina high-throughput sequencing platform to study chromatin accessibility/openness. ATAC-Seq stands for Assay for Transposase Accessible Chromatin with high-throughput sequencing. It is a high-throughput sequencing technology that uses transposase to study chromatin accessibility. The principle is to take advantage of the property of transposase Tn5 to cleave open chromatin regions and sequence the DNA sequence of the open chromatin regions captured by the Tn5 enzyme. This kit optimizes the experimental reaction system and library construction process. Compared with traditional technology, it has the advantages of wide compatibility range of cell input, short experimental cycle, high signal-to-noise ratio, and wide application range. It is especially suitable for tumor diseases, biological diseases, etc. Epigenetic research on development and aging.
